MiOA: Intervention: Community: Oral Nutrition Supplements (2023)

Author and Year:
Zhu L, Chan R, et al. 2019
PubMed ID:
Article Title:
Effects of exercise and nutrition supplementation in community-dwelling older Chinese people with sarcopenia: a randomized controlled trial.
Zhu L, Chan R, Kwok T, Cheng K, Ha A, Woo J
Age and Ageing
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Low risk
Inclusion Criteria:
Chinese older adults aged 65 years or above; ambulatory and able to travel to the testing facility; sarcopenia as defined by the Asian Working Group for Sarcopenia; recruited from community elderly centers, nursing homes and other institutional settings.
Exclusion Criteria:
Cognitive impairment as defined by the Chinese MMSE (<18); recent or concurrent participation in other clinical trials or dietary and/or exercise intervention programs; self-reported allergy to ingredients of nutrition supplement; use of medications that affect study outcomes; cancer with ongoing treatment; poorly controlled or unstable COPD, CVD, DM, or HTN; recent unhealed bone fracture (within 12 months); medical advice or conditions prohibiting exercise; major medical or psychological conditions that precluded safe participation in exercise program and/or trial.
Research Purpose:
To assess the impact of resistance exercise program targeting muscle strength and power with and without nutrition supplementation on gait speed, body composition, physical function, and quality of life.
Blinding efforts:
Single blind in manuscript, but Appendix 1 says the following: The subjects were blinded to the treatment assignment. All investigators and outcome assessors were blinded to the treatment assignment.
Study Location:
Hong Kong
Source(s) of Funding:
Please specify names of funders:
Institute of Ageing Centre for Nutritional Studies of the Chinese University of Hong Kong