MiOA: Intervention: Community: Oral Nutrition Supplements (2023)

Author and Year:
Smith TR, Cawood AL, et al. 2020
PubMed ID:
Article Title:
Ready-Made Oral Nutritional Supplements Improve Nutritional Outcomes and Reduce Health Care Use—A Randomised Trial in Older Malnourished People in Primary Care
Smith TR, Cawood AL, Walters ER, Guildford N, Stratton RJ.
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Individuals >/= 50 years, at medium or high risk of malnutrition (according to the Malnutrition Universal Screening Tool (MUST)), if the malnutrition was disease related, and they were able to eat and drink and provide consent.
Exclusion Criteria:
Galactosaemia or known lactose intolerance, those already receiving any form of nutritional support, chronic renal disease requiring dialysis, dysphagia, poorly controlled diabetes, liver failure, cancer, end of life care, residing in an institution, participation in other clinical trials, unable to provide informed consent and those not at risk for disease-related malnutrition.
Research Purpose:
This trial was conducted to investigate whether first line treatment for malnutrition using a combination of oral nutrition supplements (ONS) and dietary advice (DA) is more effective than DA alone, at improving nutritional outcomes, quality of life (QoL), healthcare use and the acceptability and satisfaction of both ONS and DA interventions, in free-living older malnourished people.
Blinding efforts:
Blinded to group allocation
Study Location:
England, UK
Source(s) of Funding:
Government, Industry
Please specify names of funders:
NIH funding, Nutricia provided supplements free of charge.