MiOA: Intervention: Community: Oral Nutrition Supplements (2023)

Author and Year:
Biesek S, Vojciechowski A, et al, 2021
PubMed ID:
Article Title:
Effects of exergames and protein supplementation on body composition and musculoskeletal function of prefrail community-dwelling older women: a randomized, controlled clinical trial.
Biesek S, Vojciechowski A, Filho J, Menezes Ferreira A, Borba V, Rabito E, Gomes A
International Journal of Environmental Research and Public Health
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
>/=65 years; scored on one or two criteria established by the frailty phenotype; “moderate” kidney functioning (i.e., a glomerular filtration rate (GFR) of 30–60 mL/min/1.73 m2); If present, type II diabetes had to be compensated (<8% glycated haemoglobin); adequate visual acuity assessed by the Snellen card (20/70 unilateral).
Exclusion Criteria:
Acute or terminal illness; metabolic instability or decompensated cardiovascular disease; cognitive deficits as determined by the Mini-Mental State Examination, and relative to school education; neurological disorders and/or traumatic-orthopedic conditions that prevented the participant from conducting the evaluations and/or the proposed exercises; type I diabetes; taking medication that might affect muscle metabolism (e.g.,corticoids) or postural balance (e.g., anticholinergics, antihistamines, benzodiazepines, calcium channel antagonists or dopamine receptor antagonists); being intolerant/allergic to milk protein; an auditory deficit that prevents understanding of verbal instructions; any serious deficiency recorded in the medical records, such as cardiac, respiratory, or hepatic deficiency; decompensated arterial hypertension (BP >/= 140/90 mmHg).
Research Purpose:
To verify the effects of progressive resistance training with exergamescombined or not with protein supplementation on pre-frailty status and criteria, body composition (appendicular muscle mass (ASM); appendicular muscle mass index (ASMI); plasma levels of (IL)-6 and musculoskeletal function (strength, mass, and architecture) in pre-frail older women.
Blinding efforts:
Due to the type of physical activity intervention, the participants knew which group they were allocated to, yet they remained blinded to the supplement they were consuming.
Study Location:
Source(s) of Funding:
Please specify names of funders:
Prodiet Medical Nutrition