Glutamine TPN
Author and Year:
Scheid C, Hermann K, Kremer G, et al. 2004
PubMed ID:
Article Title:
Randomized, double-blind, controlled study of glycyl-glutamine-dipeptide in the parenteral nutrition of patients with acute leukemia undergoing intensive chemotherapy.
Authors:
Scheid C, Hermann K, Kremer G, Holsing A, Heck G, Fuchs M, Waldschmidt D, Herrmann H, Söhngen D, Diehl V, Schwenk A
Journal:
Nutrition
Year of publication:
2004
Volume:
20
Issue:
3
Page numbers:
249-254
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Acute myeloid leukemia, scheduled to receive myelosuppressive chemotherapy or had begun chemotherapy not more than 3 d before inclusion into the study
Exclusion Criteria:
Sepsis, infection with HIV, pregnancy, severe liver or renal failure, or a known inborn error of amino acid metabolism
Research Purpose:
The aim of this study was to investigate the clinical and immunologic effects of parenteral glutamine supplementation in patients with acute leukemia.
Blinding efforts:
TPN preparations were compounded in the hospital pharmacy by a pharmacist not involved in patient care; TPN bags were labeled without indication of their glutamine content
Study Location:
Germany
Source(s) of Funding:
Not reported
Please specify names of funders: