PDM: Metabolic Syndrome (2013)

PDM: Metabolic Syndrome (2013)

• Intervention
  In adults with metabolic syndrome, what is the impact of MNT on renal outcomes?

  • Conclusion

    There were no studies identified to evaluate the impact of medical nutrition therapy (MNT) on renal outcomes in adults with metabolic syndrome.

    Intervention studies are needed regarding the effect of medical nutrition therapy on renal outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for renal measures.

  • Grade: V
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Search Plan and Results: PDM: Medical Nutrition Therapy and Metabolic Syndrome 2012
     
• Basic Research
  In adults with metabolic syndrome, what is the impact of MNT on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?

  • Conclusion

    One study regarding the impact of medical nutrition therapy (MNT) reported significant decreases in fasting blood glucose of 2.5 to 9mg per dL (0.1 to 0.5mmol per L) and in A1C of 0.12% to 0.23% in adults with metabolic syndrome. Increased frequency of visits resulted in greater improvement in fasting blood glucose.

    Additional longer-term intervention studies are needed regarding the effect of medical nutrition therapy on glycemic-related outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for impaired glucose tolerance and impaired fasting glucose.

    
    

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of MNT on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Munakata M, Honma H, Akasi M, Araki T, Kawamura T, Kubota M, Yokokawa T, Numata Y, Toyonaga T, J-STOP-MetS Study Group. Repeated counselling improves the antidiabetic effects of limited individualized lifestyle guidance in metabolic syndrome: J-STOP-METS final results. Hypertens Res. 2011; 34 (5): 612-616.
  • Search Plan and Results: PDM: Medical Nutrition Therapy and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of MNT on lipid outcomes (TG, HDL)?

  • Conclusion

    One study regarding the impact of medical nutrition therapy (MNT) reported decreases in triglycerides of 21 to 35mg per dL (0.2 to 0.4mmol per L) and increases in HDL-cholesterol of 2.4mg per dL (0.06mmol per L) in adults with metabolic syndrome. 

    Additional longer-term intervention studies are needed regarding the effect of medical nutrition therapy on lipid outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for lipid levels.

    
    

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of MNT on lipid outcomes (TG, HDL)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Munakata M, Honma H, Akasi M, Araki T, Kawamura T, Kubota M, Yokokawa T, Numata Y, Toyonaga T, J-STOP-MetS Study Group. Repeated counselling improves the antidiabetic effects of limited individualized lifestyle guidance in metabolic syndrome: J-STOP-METS final results. Hypertens Res. 2011; 34 (5): 612-616.
  • Search Plan and Results: PDM: Medical Nutrition Therapy and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of MNT on anthropometric outcomes (WC, WHR)?

  • Conclusion

    One study regarding the impact of medical nutrition therapy (MNT) reported decreases in body weight of 2.5 to 4.1kg and in waist circumference of 1.9 to 4.8cm in adults with metabolic syndrome. Increased frequency of visits resulted in greater improvement in waist circumference.

    Additional longer-term intervention studies are needed regarding the effect of medical nutrition therapy on anthropometric outcomes in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for anthropometric measures.

     
    

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of MNT on anthropometric outcomes (WC, WHR)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Munakata M, Honma H, Akasi M, Araki T, Kawamura T, Kubota M, Yokokawa T, Numata Y, Toyonaga T, J-STOP-MetS Study Group. Repeated counselling improves the antidiabetic effects of limited individualized lifestyle guidance in metabolic syndrome: J-STOP-METS final results. Hypertens Res. 2011; 34 (5): 612-616.
  • Search Plan and Results: PDM: Medical Nutrition Therapy and Metabolic Syndrome 2012
     
  In adults with metabolic syndrome, what is the impact of MNT on blood pressure?

  • Conclusion

    One study regarding the impact of medical nutrition therapy (MNT) reported decreases in systolic blood pressure of 4.9mmHg, but not diastolic blood pressure, in adults with metabolic syndrome. Increased frequency of visits resulted in greater improvement in systolic blood pressure.

    Additional longer-term intervention studies are needed regarding the effect of medical nutrition therapy on blood pressure in adults with metabolic syndrome with or without meeting the metabolic syndrome criteria for blood pressure.
    

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with metabolic syndrome, what is the impact of MNT on blood pressure?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Munakata M, Honma H, Akasi M, Araki T, Kawamura T, Kubota M, Yokokawa T, Numata Y, Toyonaga T, J-STOP-MetS Study Group. Repeated counselling improves the antidiabetic effects of limited individualized lifestyle guidance in metabolic syndrome: J-STOP-METS final results. Hypertens Res. 2011; 34 (5): 612-616.
  • Search Plan and Results: PDM: Medical Nutrition Therapy and Metabolic Syndrome 2012