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  • Intervention
    What is the long-term effectiveness in people with celiac disease of following a gluten-free dietary pattern on quality of life?
    • Conclusion
      Individuals with celiac disease demonstrate improved quality of life after compliance with a gluten-free dietary pattern for at least 1 year.  Those who have been symptom-detected rather than screen-detected demonstrated greater improvement in quality of life.  Individuals with celiac disease may not attain the same level of quality of life as the general population, due to social inconveniences of following a gluten-free dietary pattern; these issues are reported more frequently by women than men.  Those with persistent gastrointestinal symptoms, despite adherence to a gluten-free dietary pattern, also did not attain quality of life comparable to the general population. 
    • Grade: II
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.