Diabetes Prevention

PDM: Prediabetes (2013)

• Assessment
  In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?

  • Conclusion

    Limited research reports mixed results regarding the impact of type of fat intake, independent of weight loss, on fasting blood glucose levels in individuals with prediabetes.

    Limited research reports no significant impact of the type of fat intake on A1C.

    Additional longer-term intervention studies are needed to ascertain the effect of type of fat intake on glycemic outcomes in individuals with prediabetes.

     

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on glycemic-related outcomes (such as fasting blood glucose, random blood glucose, two-hour post-prandial blood glucose, A1C)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Louheranta AM, Sarkkinen ES, Vidgren HM, Schwab US, Uusitupa MIJ. Association of the fatty acid profile of serum lipids with glucose and insulin metabolism during two fat-modified diets in subjects with impaired glucose tolerance. Am J Clin Nutr. 2002; 76: 331-337. 
      • Sarkkinen E, Schwab U, Niskanen L, Hannuksela M, Savolainen M, Kervinen K, Kesaniemi A, Uusitupa MIJ. The effect of monounsaturated-fat enriched diet and polyunsaturated-fat enriched diet on lipid and glucose metabolism in subjects with impaired glucose tolerance. Eur J Clin Nutr. 1996; 50(9): 592-598.
      • Wien M, Bleich D, Raghuwanshi M, Gould-Forgerite S, Gomes J, Monahan-Couch L, Oda K. Almond consumption and cardiovascular risk factors in adults with prediabetes. J Am Coll Nutr. 2010; 29(3): 1,189-1,197.
         
  • Search Plan and Results: PDM: Fat Type and Prediabetes 2012
     
  In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on lipid outcomes (TG, HDL)?

  • Conclusion

    Limited research reports no significant impact of type of fat intake, independent of weight loss, on triglycerides or HDL cholesterol in individuals with prediabetes.

    Additional longer-term intervention studies are needed to ascertain the effect of type of fat intake on lipid outcomes in individuals with prediabetes.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on lipid outcomes (TG, HDL)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Sarkkinen E, Schwab U, Niskanen L, Hannuksela M, Savolainen M, Kervinen K, Kesaniemi A, Uusitupa MIJ. The effect of monounsaturated-fat enriched diet and polyunsaturated-fat enriched diet on lipid and glucose metabolism in subjects with impaired glucose tolerance. Eur J Clin Nutr. 1996; 50(9): 592-598.
      • Wien M, Bleich D, Raghuwanshi M, Gould-Forgerite S, Gomes J, Monahan-Couch L, Oda K. Almond consumption and cardiovascular risk factors in adults with prediabetes. J Am Coll Nutr. 2010; 29(3): 1,189-1,197.
         
  • Search Plan and Results: PDM: Fat Type and Prediabetes 2012
     
  In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on anthropometric outcomes (WC, WHR)?

  • Conclusion

    Limited research reports no significant impact of type of fat intake, independent of weight loss, on waist circumference in individuals with prediabetes.
    

    Additional longer-term intervention studies are needed to ascertain the effect of type of fat intake on anthropometric outcomes in individuals with prediabetes.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on anthropometric outcomes (WC, WHR)?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Lindstrom J, Peltonen M, Eriksson JG, Louheranta A, Fogelholm M, Uusitupa M, Tuomilehto J. High-fibre, low-fat diet predicts long-term weight loss and decreased type 2 diabetes risk: The Finnish Diabetes Prevention Study. Diabetologia, 2006; 49: 912-920.
      • Wien M, Bleich D, Raghuwanshi M, Gould-Forgerite S, Gomes J, Monahan-Couch L, Oda K. Almond consumption and cardiovascular risk factors in adults with prediabetes. J Am Coll Nutr. 2010; 29(3): 1,189-1,197.
         
  • Search Plan and Results: PDM: Fat Type and Prediabetes 2012
     
  In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on blood pressure?

  • Conclusion

    Limited research reports no significant impact of type of fat intake, independent of weight loss, on   systolic or diastolic blood pressure in individuals with prediabetes.

    Additional longer-term intervention studies are needed to ascertain the effect of type of fat intake on blood pressure in individuals with prediabetes.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In individuals with prediabetes, what is the impact of type of fat intake, independent of weight loss, on blood pressure?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Wien M, Bleich D, Raghuwanshi M, Gould-Forgerite S, Gomes J, Monahan-Couch L, Oda K. Almond consumption and cardiovascular risk factors in adults with prediabetes. J Am Coll Nutr. 2010; 29(3): 1,189-1,197.
         
  • Search Plan and Results: PDM: Fat Type and Prediabetes 2012