CD: Quality of Life (2006)
What is the long-term effectiveness in people with celiac disease of following a gluten-free dietary pattern on quality of life?
Individuals with celiac disease demonstrate improved quality of life after compliance with a gluten-free dietary pattern for at least 1 year. Those who have been symptom-detected rather than screen-detected demonstrated greater improvement in quality of life. Individuals with celiac disease may not attain the same level of quality of life as the general population, due to social inconveniences of following a gluten-free dietary pattern; these issues are reported more frequently by women than men. Those with persistent gastrointestinal symptoms, despite adherence to a gluten-free dietary pattern, also did not attain quality of life comparable to the general population.
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
Evidence Summary: What is the long-term effectiveness of following a gluten-free dietary pattern on quality of life?
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Ciacci C, Iavarone A, Siniscalchi M, Romano R, De Rosa A. Psychological dimensions of celiac disease: toward an integrated approach. Dig Dis Sci. 2002; 47 (9): 2,082-2,087.
- Ciacci C, D'Agate C, De Rosa A, Franzese C, Errichiello S, Gasperi V, Pardi A, Quagliata D, Visentini S, Greco L. Self-rated quality of life in celiac disease. Dig Dis Sci 2003; 48(11): 2216-2220.
- Fera T, Cascio B, Angelini G, Martini S, Guidetti CS. Affective disorders and quality of life in adult celiac disease patients on a gluten-free diet. Eur J Gastroenterol Hepatol 2003; 15(12): 1287-1292.
- Green PHR, Stavropoulos SN, Panagi SG, Goldstein SL, McMahon DJ, Absan H, Neugut AI. Characteristics of adult celiac disease in the USA: results of a national survey. Am J Gastroenterol 2001; 96(1):126-131.
- Hallert C, Granno C, Hulten S, Midhagen G, Strom M, Svensson H, Valdimarsson T. Living with celiac disease: controlled study of the burden of illness. Scand J Gastroenterol 2002; 37: 39-42.
- Hallert C, Sandlund O, Broqvist M. Perceptions of health-related quality of life of men and women living with celiac disease. Scand J Caring Sci 2003; 17(3): 301-307.
- Hallert C, Granno C, Grant C, Hulten S, Midhagen G, Strom M, Svensson H, Valdimarsson T, Wickstrom T. Quality of life of adult celiac patients treated for 10 years. Scand J Gastroenterol 1998; 33(9): 933-938.
- Johnston SD, Rodgers C, Watson RGP. Quality of life in screen-detected and typical coeliac disease and the effect of excluding dietary gluten. Eur J Gastroenterol Hepatol 2004; 16(12): 1281-1286.
- Lee A, Newman JM. Celiac diet: its impact on quality of life. J Am Diet Assoc 2003; 103: 1533-1535.
- Mustalahti K, Lohiniemi S, Collin P, Vuolteenaho N, Laippala P, Maki M. Gluten-free diet and quality of life in patients with screen-detected celiac disease. Eff Clin Pract 2002; 5(3): 105-113.
- Usai P, Minerba L, Marini B, Cossu R, Spada S, Carpiniello B, Cuomo R, Boy MF. Case control study on health-related quality of life in adult celiac disease. Digest Liver Dis 2002; 34 (8): 547-552.
- Zarkadas M, Cranney A, Case S, Molloy M, Switzer C, Graham D, Butzner JD, Rashid M, Warren RE, Burrows V. The impact of a gluten-free diet on adults with celiac disease: results of a national survey. J Hum Nutr Dietet 2006; 19:41-49.
Search Plan and Results: CD: Quality of Life 2007