• Intervention
    How does the inclusion of wheat starch-based gluten-free foods (as defined by the Codex Alimentarius), in a dietary pattern for people with celiac disease, impact the effectiveness and acceptability of their dietary pattern (as compared to a gluten-free diet comprised solely of naturally gluten-free foods, as defined by Codex)?
    • Conclusion

      Studies have shown that both natural and wheat starch-based gluten-free diets produce similar histological and clinical recovery in people with celiac disease. Overall compliance with a gluten-free diet may be more important than the specific type of diet followed (i.e., natural or wheat starch-based), as evidenced by the incomplete bowel mucosal recovery and positive serology generally seen in those study subjects with dietary lapses. Further research regarding the acceptability of wheat starch-based gluten-free foods and the threshold level of tolerance for gluten is needed.

    • Grade: III
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.