Hypertension

HTN: Garlic (2007)

• Intervention
  What is the relationship between garlic intake and blood pressure in healthy and hypertensive adults?

  • Conclusion

    The effect of garlic intake on blood pressure is unclear, as the results of five studies are conflicting.

  • Grade: III
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: What evidence suggests a relationship between garlic intake and blood pressure in healthy and hypertensive adults?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Dhawan V, Jain S. Effect of garlic supplementation on oxidized low density lipoproteins and lipid peroxidation in patients of essential hypertension. Mol Cell Biochem. 2004; 266 (1-2): 109-115.
      • Durak I, Kavutcu M, Aytac B, Avci A, Devrim E, Ozbek H, Ozturk HS. Effects of garlic extract consumption on blood lipid and oxidant/antioxidant parameters in humans with high blood cholesterol. J Nutr Biochem. 2004; 15 (6): 373-377.
      • Qidwai W, Qureshi R, Hasan SN, Azam SI. Effect of dietary garlic (Allium sativum) on the blood pressure in humans - a pilot study. J Pak Med Assoc. 2000; 50 (6): 204-207.
      • Turner B, Molgaard C, Marckmann P. Effect of garlic (Allium sativum) powder tablets on serum lipids, blood pressure and arterial stiffness in normo-lipidaemic volunteers: a randomised, double-blind, placebo-controlled trial. Br J Nutr. 2004; 92 (4): 701-706.
        
      • Zhang XH, Lowe D, Giles P, Fell S, Board AR, Baughan JA, Connock MJ, Maslin DJ. A randomized trial of the effects of garlic oil upon coronary heart disease risk factors in trained male runners. Blood Coagul Fibrinolysis. 2001; 12 (1): 67-74.
  • Search Plan and Results: Garlic 2005