HTN: Medical Nutrition Therapy (2022-24)
Author and Year:
Oberman A, Wassertheil-Smoller S, Langford H, et al. 1990
PubMed ID:
Article Title:
Pharmacologic and nutritional treatment of mild hypertension: changes in cardiovascular risk status.
Authors:
Oberman A, Wassertheil-Smoller S, Langford H, Blaufox M, Davis B, Blaszkowski T, Zimbaldi N, Hawkins C
Journal:
Annals of Internal Medicine
Year of publication:
1990
Volume:
112
Issue:
2
Page numbers:
89-95
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Ages 21-65 years. Preliminary screening: blood pressure of 100 mmHg who were already on antihypertensive medication or 90-104 mmHg for those not on treatment. Second screening: diastolic blood pressure from 90 to 100 mm Hg and weight of 110% to 160% of ideal weight.
Exclusion Criteria:
Evidence of myocardial infarction, stroke, bronchial asthma, a serum creatinine level of 176.8 mmol/d (2.0 mg/dL) or greater, diabetes requiring insulin therapy, allergy to thiazides or beta-blockers, or likelihood of difficulty in complying with the intervention.
Research Purpose:
To evaluate the 6-month change in cardiovascular risk as a function of diet and drug therapy for mild hypertension.
Blinding efforts:
See Risk of Bias
Study Location:
United States
Source(s) of Funding:
Government
Please specify names of funders:
National Heart, Lung and Blood Institute of the NIH.