NPA-GP: Quality of Life and Anxiety/Depression (2021)

Author and Year:
Ruusunen A, Voutilainen S, et al, 2012
PubMed ID:
Article Title:
How does lifestyle intervention affect depressive symptoms? Results from the Finnish Diabetes Prevention Study.
Ruusunen A, Voutilainen S, Karhunen L, Lehto S, Tolmunen T, Keinänen-Kiukaanniemi S, Eriksson J, Tuomilehto J, Uusitupa M, Lindström J
Diabetic Medicine
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
BMI over 25 kg/m2; age 40–64 years; impaired glucose tolerance on the basis of the mean values of two oral glucose tolerance tests defined as 2-h plasma glucose 7.8-11.0 mmol/L with fasting bg <7.8 mmol/L.
Exclusion Criteria:
Previous diagnosis of type 2 diabetes mellitus - other than gestational diabetes; regularly in a vigorous exercise programme; receiving treatment to lower blood glucose; any chronic disease making a 6-year survival improbable; any medical characteristics likely to interfere with participation in the study; with unbalance clinical conditions such as thyroid and liver disease (interfere with glucose metabolism).
Research Purpose:
The main aim of the study was to assess the efficacy of lifestyle modification on preventing or delaying the onset of Type 2 diabetes in people with impaired glucose tolerance.
Blinding efforts:
Study Location:
Source(s) of Funding:
Government, University/Hospital, Not-for-profit
Please specify names of funders:
Finnish Graduate School of Psychiatry Yrjo Jahnsson Foundation JuhoVainio Foundation Academy of Finland Novo Nordisk Foundation SalWeResearch Program for Mind and Body
Trial Name if applicable:
Finnish Diabetes Prevention Study, NCT00518167