NPA-GP: Adverse Events (2021)

Author and Year:
Campbell K, Foster-Schubert K, et al, 2012
PubMed ID:
Article Title:
Reduced-calorie dietary weight loss, exercise, and sex hormones in postmenopausal women: randomized controlled trial.
Campbell K, Foster-Schubert K, Alfano C, Wang C, Wang C, Duggan C, Mason C, Imayama I, Kong A, Xiao L, Bain C, Blackburn G, Stanczyk F, McTiernan A
Journal of Clinical Oncology
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Participants were postmenopausal (no menstrual cycles for >/= 1 year or follicle-stimulating hormone level of >23.0 IU/L for women 50 to 59 years of age without a uterus), age 50 to 75 years, body mass index > /= 25.0 kg/m2 (>/= 23.0 kg/m2 if Asian-American), and participating in less than 100 minutes/wk in moderate-intensity physical activity.
Exclusion Criteria:
Exclusion criteria included use of estrogen, progesterone, or testosterone hormones (past 3 months); history of breast cancer or other serious medical conditions; diabetes, fasting glucose >/= 126 mg/dL, or use of diabetes medications; more than two alcohol drinks/d; current smoker; or current use of weight loss medications or programs.
Research Purpose:
To evaluate the individual and combined effects of a reduced-calorie weight loss diet and exercise on serum sex hormones in overweight and obese postmenopausal women.
Blinding efforts:
Study Location:
Source(s) of Funding:
Please specify names of funders:
The Nutrition and Exercise for Women (NEW) trial was supported by R01 CA105204-01A1 from the National Cancer Institute (NCI).
Trial Name if applicable: