NPA-GP: Glucose Outcomes (2021)
Author and Year:
Mason C, Foster-Schubert K, et al, 2011
Dietary weight loss and exercise effects on insulin resistance in postmenopausal women.
Mason C, Foster-Schubert K, Imayama I, Kong A, Xiao L, Bain C, Campbell K, Wang C, Duggan C, Ulrich C, Alfano C, Blackburn G, McTiernan A
American Journal of Preventive Medicine
Year of publication:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Participants were overweight or obese (BMI >/=25.0, >/=23.0 if Asian American) postmenopausal women (aged 50–75 years) from the greater-Seattle area who were not meeting physical activity guidelines.
Specific exclusion criteria included diagnosed diabetes, fasting blood glucose >/=26 mg/dL or use of diabetes medications; use of postmenopausal hormones; history of other serious medical condition(s); alcohol intake >2 drinks/day; current smoking; contraindication to the study interventions for any reason (e.g., abnormal exercise tolerance test); participation in another structured weight loss program; or use of weight-loss medications.
The aim of the study was to investigate the independent and combined effects of dietary weight loss and exercise on insulin sensitivity and restoration of normal fasting glucose in middle-aged and older women.
Source(s) of Funding:
Please specify names of funders:
Trial Name if applicable: