NPA-GP: Glucose Outcomes (2021)

Author and Year:
Mason C, Foster-Schubert K, et al, 2011
PubMed ID:
Article Title:
Dietary weight loss and exercise effects on insulin resistance in postmenopausal women.
Authors:
Mason C, Foster-Schubert K, Imayama I, Kong A, Xiao L, Bain C, Campbell K, Wang C, Duggan C, Ulrich C, Alfano C, Blackburn G, McTiernan A
Journal:
American Journal of Preventive Medicine
Year of publication:
2011
Volume:
41
Issue:
4
Page numbers:
366-75
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Participants were overweight or obese (BMI >/=25.0, >/=23.0 if Asian American) postmenopausal women (aged 50–75 years) from the greater-Seattle area who were not meeting physical activity guidelines.
Exclusion Criteria:
Specific exclusion criteria included diagnosed diabetes, fasting blood glucose >/=26 mg/dL or use of diabetes medications; use of postmenopausal hormones; history of other serious medical condition(s); alcohol intake >2 drinks/day; current smoking; contraindication to the study interventions for any reason (e.g., abnormal exercise tolerance test); participation in another structured weight loss program; or use of weight-loss medications.
Research Purpose:
The aim of the study was to investigate the independent and combined effects of dietary weight loss and exercise on insulin sensitivity and restoration of normal fasting glucose in middle-aged and older women.
Blinding efforts:
Study Location:
USA
Source(s) of Funding:
Government
Please specify names of funders:
NIH
Trial Name if applicable:
NEW