NPA-GP: Adverse Events (2021)
Author and Year:
Ma J, Rosas L, et al, 2019
Effect of integrated behavioral weight loss treatment and problem-solving therapy on body mass index and depressive symptoms among patients with obesity and depression: the RAINBOW randomized clinical trial.
Ma J, Rosas L, Lv N, Xiao L, Snowden M, Venditti E, Lewis M, Goldhaber-Fiebert J, Lavori P
Journal of the American Medical Association
Year of publication:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Adults of any sex and race/ethnicity were eligible if they (1) had a body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) of 30 or greater (?27 for Asian adults), (2) had depressive symptoms defined by a 9-itemPatientHealth Questionnaire (PHQ-9) score of 10 or greater,16,17 and (3) did not have any serious comorbidities or meet any other exclusion criteria (eg, pregnancy, inability to speak or read English, and plan to relocate).
Those with significant medical (e.g., type 2 diabetes mellitus or cardiovascular disease) or psychiatric comorbidities (e.g., psychotic or bipolar disorders) or special lifestyle circumstances
To test the hypothesis that an integrated collaborative care intervention would significantly improve both obesity and depression at 12 months compared with usual care.
Source(s) of Funding:
Please specify names of funders:
This research was supported by award R01HL119453 from the National Heart, Lung, and Blood Institute and internal funding from the Palo Alto Medical Foundation Research Institute and the University of Illinois, Chicago.
Trial Name if applicable: