NPA-GP: Adverse Events (2021)
Author and Year:
Ma J, Rosas L, et al, 2019
PubMed ID:
Article Title:
Effect of integrated behavioral weight loss treatment and problem-solving therapy on body mass index and depressive symptoms among patients with obesity and depression: the RAINBOW randomized clinical trial.
Authors:
Ma J, Rosas L, Lv N, Xiao L, Snowden M, Venditti E, Lewis M, Goldhaber-Fiebert J, Lavori P
Journal:
Journal of the American Medical Association
Year of publication:
2019
Volume:
321
Issue:
9
Page numbers:
869-879
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Low risk
Inclusion Criteria:
Adults of any sex and race/ethnicity were eligible if they (1) had a body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) of 30 or greater (?27 for Asian adults), (2) had depressive symptoms defined by a 9-itemPatientHealth Questionnaire (PHQ-9) score of 10 or greater,16,17 and (3) did not have any serious comorbidities or meet any other exclusion criteria (eg, pregnancy, inability to speak or read English, and plan to relocate).
Exclusion Criteria:
Those with significant medical (e.g., type 2 diabetes mellitus or cardiovascular disease) or psychiatric comorbidities (e.g., psychotic or bipolar disorders) or special lifestyle circumstances
Research Purpose:
To test the hypothesis that an integrated collaborative care intervention would significantly improve both obesity and depression at 12 months compared with usual care.
Blinding efforts:
Study Location:
USA
Source(s) of Funding:
Government, University/Hospital
Please specify names of funders:
This research was supported by award R01HL119453 from the National Heart, Lung, and Blood Institute and internal funding from the Palo Alto Medical Foundation Research Institute and the University of Illinois, Chicago.
Trial Name if applicable:
RAINBOW