CRDA: Inflammatory Marker Outcomes (2023)

Author and Year:
Favricatore A, Wadden T, el al, 2012
PubMed ID:
Article Title:
Targeting dietary fat or glycemic load in the treatment of obesity and type 2 diabetes: a randomized controlled trial.
Fabricatore A, Wadden T, Ebbeling C, Thomas J, Stallings V, Schwartz S, Ludwig D
Diabetes Research and Clinical Practice
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Men and women; 18 -65 years; diagnosis of type 2 diabetes; body mass index (BMI) of 27 to 45 kg/m2
Exclusion Criteria:
Type 1 diabetes; uncontrolled hypertension (>160/100 mm Hg); thyroid disease; unstable angina; malignant arrhythmias; myocardial infarction in the past year; cancer (active or in remission < 5 years; clinically significant psychosocial impairment; any history of cerebrovascular, renal, hepatic or protein-wasting diseases; women who were pregnant or lactating.
Research Purpose:
To compare the effects of low-fat and low glycemic load (GL) diets, delivered in the context of a lifestyle modification program for weight loss in participants with type 2 diabetes mellitus (DM).
Blinding efforts:
Blinding to treatment condition was not possible.
Study Location:
University of Pennsylvania Center for Weight and Eating Disorders, Philadelphia, PA, USA
Source(s) of Funding:
Government, Industry
Please specify names of funders:
National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Research Resources, Calorie King