CRDA: Lipid Outcomes (2023)
Author and Year:
Larsen R, Mann N, et al. 2011
PubMed ID:
Article Title:
The effect of high-protein, low-carbohydrate diets in the treatment of type 2 diabetes: a 12 month randomised controlled trial.
Authors:
Larsen R, Mann N, Maclean E, Shaw J
Journal:
Diabetologia
Year of publication:
2011
Volume:
54
Issue:
4
Page numbers:
731-740
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Low
Inclusion Criteria:
Aged 30-75 years; overweight/obese individuals (BMI 27-40 kg/m2); HbA1c 6.5-10%
Exclusion Criteria:
Significant heart disease (unstable angina, cardiac failure, or recent myocardial infarction or coronary intervention); stroke within the previous 3 months; renal disease (proteinuria or serum creatinine >0.13 mmol/l); liver disease; malignancy.
Research Purpose:
To determine whether high-protein diets are superior to high-carbohydrate diets for improving glycemic control in individuals with type 2 diabetes.
Blinding efforts:
Study personnel who enrolled participants were blinded to the sequence allocation. Dietary assignment was performed by a third party on the day of the initial dietary counselling visit.
Study Location:
Diabetes Specialist Clinic (Melbourne, VIC, Australia).
Source(s) of Funding:
Government, Industry
Please specify names of funders:
Nutritional research grant from Meat and Livestock Australia (MLA). NHMRC Fellowship 586623.