CRDA: Anthropometric Outcomes (2023)

Author and Year:
Fechner E, Bilet L, et al. 2020
PubMed ID:
Article Title:
Effects of a whole diet approach on metabolic flexibility, insulin sensitivity and postprandial glucose responses in overweight and obese adults - A randomized controlled trial.
Fechner E, Bilet L, Peters H, Hiemstra H, Jacobs D, Op 't Eyndt C, Kornips E, Mensink R, Schrauwen P
Clinical Nutrition
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Age 50-70 years old; healthy; overweight or obese (BMI 25-35 kg/m2)
Exclusion Criteria:
Any medical condition which might have affected the study measurements, i.e. metabolic disorders, including type 1 and type 2 diabetes, gastrointestinal dysfunction, gastrointestinal surgery or inflammatory diseases); fasting plasma glucose of >6.9 mmol/l; smoking' shift work; excessive alcohol consumption (>7 consumptions per week); medically prescribed diets; slimming diets' being vegetarian; doing more than 2.5 hours of moderate to vigorous physical activity per week; reported weight loss or gain of >10% in the past 6 months; medication which could have interfered with the study measurements.
Research Purpose:
To assess the effect of a healthy diet, as compared to a typical Western diet, on several fasting and postprandial markers of metabolic flexibility and insulin sensitivity
Blinding efforts:
Study Location:
The Netherlands
Source(s) of Funding:
Please specify names of funders:
Unilever Food Innovation Center