CRDA: Lipid Outcomes (2023)
Author and Year:
de Melo C, Dos Santos Quaresma M, et al. 2021
PubMed ID:
Article Title:
One-month of a low-energy diet, with no additional effect of high-protein, reduces Obstructive Sleep Apnea severity and improve metabolic parameters in obese males.
Authors:
de Melo C, Dos Santos Quaresma M, Del Re M, Ribeiro S, Moreira Antunes H, Togeiro S, Tufik S, de Mello M
Journal:
Clinical Nutrition ESPEN
Year of publication:
2021
Volume:
42
Issue:
Page numbers:
82-89
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Male; 30-55 years old; obstructive sleep apnea diagnosed by polysomnography.
Exclusion Criteria:
Age <30 and >55 years; mild sleep apnea severity (AHI <5 events/hour); use of any other obstructive sleep apnea treatment such as CPAP, drugs or oral appliance therapy; using drugs for metabolic diseases such as diabetes mellitus, dyslipidemia, or thyroid diseases; shift workers; other sleep disturbances rather than/in addition to OSA; smoking; physical exercise practitioners; individuals with eating disorders; physical exercise practitioners
Research Purpose:
To evaluate the effects of a low-energy, high-protein diet on obese men's OSA (Obstructive Sleep Apnea) severity and metabolic parameters. We tested the hypothesis that increased protein intake during an energy-restricted diet results in better OSA and metabolic improvements due to increased energy expenditure and fat/fat-free mass relation than a normal-protein-content diet in OSA patients.
Blinding efforts:
Not reported
Study Location:
Sao Paulo, Brazil
Source(s) of Funding:
Government
Please specify names of funders:
Associaçao Fundo de Incentivo?a Pesquisa (AFIP), Centro de Estudos em Psicobiologia e Exercício(CEPE), CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnologico), CAPES (Coordenaçao de Aperfeiçoamento Pessoal de Nível Superior), FAPESP (Fundaçao de Amparo?a pesquisa do Estadode Sao Paulo) Grant number: 2012/09700-2