CRDA: Other Outcomes (2023)

Author and Year:
Mateo-Gallego R, Marco-Benedi V, et al. 2017
PubMed ID:
Article Title:
Energy-restricted, high-protein diets more effectively impact cardiometabolic profile in overweight and obese women than lower-protein diets.
Mateo-Gallego R, Marco-Benedí V, Perez-Calahorra S, Bea A, Baila-Rueda L, Lamiquiz-Moneo I, de Castro-Orós I, Cenarro A,Civeira F
Clinical Nutrition
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Inclusion Criteria:
Women; age 18-80 years; BMI 27.5-45 kg/m2; steady weight (±3 kg) in the previous 3 months.
Exclusion Criteria:
Uncontrolled hypothyroidism, type-2 diabetes (glycated hemoglobin >8%); any other disease that could interfere w/ ability to comply w/study protocol; current lipid-lowering or anti-diabetic drugs; taking supplements of phytosterols, omega3-fatty acids, or any obesity drug
Research Purpose:
To assess the effects of three energy-reduced diets with different percentages of calories from protein (20%, 27%, and 35%) on weight loss and lipids.
Blinding efforts:
Participants were blinded to their assigned macronutrient composition. The dietician who formulated the diets and carried out the individual consultations was aware of each participant's group assignment. The rest of the staff were blinded to that information.
Study Location:
Hospital Universitario Miguel Servet, Zaragoza, Spain
Source(s) of Funding:
Please specify names of funders:
Teruel Investment Fund from Ministerio de Ciencia e Innovacion, Spain. Grants from the Spanish Ministry of Health (FIS PI12/01087 and RETIC RIC RD12/0042/0055) also supported this work.