CRDA: Anthropometric Outcomes (2023)

Author and Year:
McClain A, Otten J, et al. 2013
PubMed ID:
Article Title:
Adherence to a low-fat vs. low-carbohydrate diet differs by insulin resistance status.
McClain A, Otten J,vHekler E,vGardner C
Diabetes, Obesity & Metabolism
Year of publication:
Page numbers:
Study Design:
Randomized Controlled Trial
Risk of Bias Assessment Rating:
Some concerns
Inclusion Criteria:
Premenopausal women; age 25 to 50 years; BMI 27 to 40; stable body weight over the previous 2 months; medication was stable for at least 3 months
Exclusion Criteria:
Self-reported hypertension (except for those whose blood pressure was stable using antihypertension medications); type 1 or2 diabetes mellitus; heart, renal, or liver disease; cancer or active neoplasms; hyyperthyroidism unless treated and under control; any medication use known to affect weight/energy expenditure; alcohol intake of at least 3 drinks/d; pregnancy; lactation; no menstrual period in the previous 12 months; plans to become pregnant within the next year.
Research Purpose:
To determine if adherence to a LF-diet versus LC-diet differs between insulin-resistant (IR) and insulin-sensitive (IS) participants.
Blinding efforts:
Study Location:
CA, United States
Source(s) of Funding:
Please specify names of funders:
National Institutes of Health (NIH) Human Health Service Grant, General Clinical Research Centers, National Center for Research Resources, National Heart, Lung, and Blood Institute.