CRDA: Inflammatory Marker Outcomes (2023)

CRDA: Inflammatory Marker Outcomes (2023)

• Intervention
  In adults with overweight or obesity and metabolic dysfunction-associated steatotic liver disease (MASLD), what is the effect of carbohydrate (CHO) restriction compared to higher CHO diets on C-reactive protein?

  • Conclusion

    Evidence suggests that intake of a moderate-carbohydrate (CHO) diet compared to a slightly higher moderate-CHO intake (↑0.9% of total daily energy intake) may have no effect on C-reactive protein in adults with overweight or obesity and metabolic dysfunction-associated steatotic liver disease (MASLD).

  • Grade: Low (C)
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with overweight or obesity and metabolic dysfunction-associated steatotic liver disease (MASLD), what is the effect of carbohydrate (CHO) restriction compared to higher CHO diets on C-reactive protein?
    • Detail
    • Worksheets
      • Marin-Alejandre B, Abete I, Cantero I, Monreal J, Elorz M,Herrero J, Benito-Boillos A, Quiroga J, Martinez-Echeverria A, Uriz-Otano J, Huarte-Muniesa M,T ur J, Martinez J, Zulet M. The Metabolic and Hepatic Impact of Two Personalized Dietary Strategies in Subjects with Obesity and Nonalcoholic Fatty Liver Disease: The Fatty Liver in Obesity (FLiO) Randomized Controlled Trial. Nutrients 2019; 11:
  • Search Plan and Results: CRDA: Overweight or Obesity and MASLD 2023