MiOA: Intervention: Post-Discharge: Oral Nutrition Supplements (2023)
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Intervention
In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on calorie and protein intake?
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Conclusion
Oral nutrition supplements may result in an increase in calorie and protein intake in older adults discharged from acute care to the community.
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Grade: Moderate (B)
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
-
Evidence Summary: In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on calorie and protein intake?
- Detail
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Worksheets
- Edington J, Barnes R, Bryan F, Dupree E, Frost G, Hickson M, Lancaster J, Mongia S, Smith J, Torrance A, West R, Pang F, Coles S. A prospective randomised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes. Clinical Nutrition (Edinburgh, Scotland) 2004; 23:195-204
- Gade J, Beck A, Andersen H, Christensen B, Rønholt F, Klausen T, Vinther A, Astrup A. Protein supplementation combined with low-intensity resistance training in geriatric medical patients during and after hospitalisation: a randomised, double-blind, multicentre trial. The British Journal of Nutrition 2019; 122:1006-1020
- Loman B, Luo M, Baggs G, Mitchell D, Nelson J, Ziegler T, Deutz N, Matarese L. Specialized high-protein oral nutrition supplement improves home nutrient intake of malnourished older adults without decreasing usual food intake. Journal of Parenteral and Enteral Nutrition 2019; 43:794-802
- McMurdo M, Price R, Shields M, Potter J, Stott D. Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. Journal of the American Geriatrics Society 2009; 57:2239-2245
- Neelemaat F, Lips P, Bosmans J, Thijs A, Seidell J, van Bokhorst-de van der Schueren M. Short-term oral nutritional intervention with protein and vitamin D decreases falls in malnourished older adults. Journal of the American Geriatrics Society 2012; 60:691-9
- Price R, Daly F, Pennington C, McMurdo M. Nutritional supplementation of very old people at hospital discharge increases muscle strength: a randomised controlled trial. Gerontology 2005; 51:179-185
- Detail
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Search Plan and Results: MiOA: Intervention Oral Nutrition Supplements 2023
In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on weight and BMI?-
Conclusion
In older adults discharged from acute care to the community, oral nutrition supplement intake may not have an effect on body weight or body mass index.
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Grade: Moderate (B)
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
-
Evidence Summary: In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on weight and BMI?
- Detail
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Worksheets
- Amasene, M; Besga, A; Echeverria, I; Urquiza, M; Ruiz, J; Rodriguez-Larrad, A; Aldamiz, M; Anaut, P; Irazusta, J; and Labayen, I. Effects of leucine-enriched whey protein supplementation on physical function in post-hospitalized older adults participating in 12-Weeks of resistance training program: a randomized controlled trial. Nutrients 2019; 11:2337-2352
- Deer R, Dickinson J, Baillargeon J, Fisher S, Raji M, Volpi E. A Phase I Randomized Clinical Trial of Evidence-Based, Pragmatic Interventions to Improve Functional Recovery After Hospitalization in Geriatric Patients. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2019; 74:1628-1636
- Edington J, Barnes R, Bryan F, Dupree E, Frost G, Hickson M, Lancaster J, Mongia S, Smith J, Torrance A, West R, Pang F, Coles S. A prospective randomised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes. Clinical Nutrition (Edinburgh, Scotland) 2004; 23:195-204
- Feldblum I, German L, Castel H, Harman-Boehm I, Shahar D. Individualized nutritional intervention during and after hospitalization: the nutrition intervention study clinical trial. Journal of the American Geriatrics Society 2011; 59:10-17
- McMurdo M, Price R, Shields M, Potter J, Stott D. Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. Journal of the American Geriatrics Society 2009; 57:2239-2245
- Neelemaat F, Bosmans J, Thijs A, Seidell J, van Bokhorst-de van der Schueren M. Post-discharge nutritional support in malnourished elderly individuals improves functional limitations. Journal of the American Medical Directors Association 2011; 12:295-301
- Neelemaat F, Lips P, Bosmans J, Thijs A, Seidell J, van Bokhorst-de van der Schueren M. Short-term oral nutritional intervention with protein and vitamin D decreases falls in malnourished older adults. Journal of the American Geriatrics Society 2012; 60:691-9
- Persson M, Hytter-Landahl A, Brismar K, Cederholm T. Nutritional supplementation and dietary advice in geriatric patients at risk of malnutrition. Clinical Nutrition (Edinburgh, Scotland) 2007; 26:216-224
- Price R, Daly F, Pennington C, McMurdo M. Nutritional supplementation of very old people at hospital discharge increases muscle strength: a randomised controlled trial. Gerontology 2005; 51:179-185
- Volkert D, Hübsch S, Oster P, Schlierf G. Nutritional support and functional status in undernourished geriatric patients during hospitalization and 6-month follow-up. Aging (Milan, Italy) 1996; 8:386-95
- Detail
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Search Plan and Results: MiOA: Intervention Oral Nutrition Supplements 2023
In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on nutrition status measured by valid nutrition assessment?-
Conclusion
Oral nutrition supplement intake may improve nutrition status measured by valid nutrition assessment in malnourished older adults discharged from acute care to the community. However, the impact on healthy older adults could not be determined due to insufficient evidence.
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Grade: Low (C)
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
-
Evidence Summary: In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on nutrition status measured by valid nutrition assessment?
- Detail
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Worksheets
- Amasene, M; Besga, A; Echeverria, I; Urquiza, M; Ruiz, J; Rodriguez-Larrad, A; Aldamiz, M; Anaut, P; Irazusta, J; and Labayen, I. Effects of leucine-enriched whey protein supplementation on physical function in post-hospitalized older adults participating in 12-Weeks of resistance training program: a randomized controlled trial. Nutrients 2019; 11:2337-2352
- Deutz N, Matheson E, Matarese L, Luo M, Baggs G, Nelson J, Hegazi R, Tappenden K, Ziegler T. Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: A randomized clinical trial. Clinical Nutrition (Edinburgh, Scotland) 2016; 35:18-26
- Detail
-
Search Plan and Results: MiOA: Intervention Oral Nutrition Supplements 2023
In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on physical function?-
Conclusion
In older adults discharged from acute care to the community, oral nutrition supplement intake does not likely have an effect on functional status (ADLs, gait speed, handgrip strength).
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Grade: Low (C)
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
-
Evidence Summary: In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on physical function?
- Detail
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Worksheets
- Amasene, M; Besga, A; Echeverria, I; Urquiza, M; Ruiz, J; Rodriguez-Larrad, A; Aldamiz, M; Anaut, P; Irazusta, J; and Labayen, I. Effects of leucine-enriched whey protein supplementation on physical function in post-hospitalized older adults participating in 12-Weeks of resistance training program: a randomized controlled trial. Nutrients 2019; 11:2337-2352
- Deer R, Dickinson J, Baillargeon J, Fisher S, Raji M, Volpi E. A Phase I Randomized Clinical Trial of Evidence-Based, Pragmatic Interventions to Improve Functional Recovery After Hospitalization in Geriatric Patients. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 2019; 74:1628-1636
- Deutz N, Matheson E, Matarese L, Luo M, Baggs G, Nelson J, Hegazi R, Tappenden K, Ziegler T. Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: A randomized clinical trial. Clinical Nutrition (Edinburgh, Scotland) 2016; 35:18-26
- Edington J, Barnes R, Bryan F, Dupree E, Frost G, Hickson M, Lancaster J, Mongia S, Smith J, Torrance A, West R, Pang F, Coles S. A prospective randomised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes. Clinical Nutrition (Edinburgh, Scotland) 2004; 23:195-204
- Gade J, Beck A, Andersen H, Christensen B, Rønholt F, Klausen T, Vinther A, Astrup A. Protein supplementation combined with low-intensity resistance training in geriatric medical patients during and after hospitalisation: a randomised, double-blind, multicentre trial. The British Journal of Nutrition 2019; 122:1006-1020
- McMurdo M, Price R, Shields M, Potter J, Stott D. Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. Journal of the American Geriatrics Society 2009; 57:2239-2245
- Neelemaat F, Bosmans J, Thijs A, Seidell J, van Bokhorst-de van der Schueren M. Post-discharge nutritional support in malnourished elderly individuals improves functional limitations. Journal of the American Medical Directors Association 2011; 12:295-301
- Neelemaat F, Bosmans J, Thijs A, Seidell J, van Bokhorst-de van der Schueren M. Oral nutritional support in malnourished elderly decreases functional limitations with no extra costs. Clinical Nutrition (Edinburgh, Scotland) 2012; 31:183-90
- Neelemaat F, Lips P, Bosmans J, Thijs A, Seidell J, van Bokhorst-de van der Schueren M. Short-term oral nutritional intervention with protein and vitamin D decreases falls in malnourished older adults. Journal of the American Geriatrics Society 2012; 60:691-9
- Persson M, Hytter-Landahl A, Brismar K, Cederholm T. Nutritional supplementation and dietary advice in geriatric patients at risk of malnutrition. Clinical Nutrition (Edinburgh, Scotland) 2007; 26:216-224
- Price R, Daly F, Pennington C, McMurdo M. Nutritional supplementation of very old people at hospital discharge increases muscle strength: a randomised controlled trial. Gerontology 2005; 51:179-185
- Volkert D, Hübsch S, Oster P, Schlierf G. Nutritional support and functional status in undernourished geriatric patients during hospitalization and 6-month follow-up. Aging (Milan, Italy) 1996; 8:386-95
- Detail
-
Search Plan and Results: MiOA: Intervention Oral Nutrition Supplements 2023
In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on mortality?-
Conclusion
In older adults discharged from acute care to the community, oral nutrition supplements are likely to result in little to no difference in mortality.
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Grade: Moderate (B)
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
-
Evidence Summary: In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on mortality?
- Detail
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Worksheets
- Deutz N, Matheson E, Matarese L, Luo M, Baggs G, Nelson J, Hegazi R, Tappenden K, Ziegler T. Readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutritional supplement: A randomized clinical trial. Clinical Nutrition (Edinburgh, Scotland) 2016; 35:18-26
- Edington J, Barnes R, Bryan F, Dupree E, Frost G, Hickson M, Lancaster J, Mongia S, Smith J, Torrance A, West R, Pang F, Coles S. A prospective randomised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes. Clinical Nutrition (Edinburgh, Scotland) 2004; 23:195-204
- Gade J, Beck A, Andersen H, Christensen B, Rønholt F, Klausen T, Vinther A, Astrup A. Protein supplementation combined with low-intensity resistance training in geriatric medical patients during and after hospitalisation: a randomised, double-blind, multicentre trial. The British Journal of Nutrition 2019; 122:1006-1020
- Neelemaat F, van Keeken S, Langius J, de van der Schueren M, Thijs A, Bosmans J. Survival in malnourished older patients receiving post-discharge nutritional support; long-term results of a randomized controlled trial. The Journal of Nutrition, Health & Aging 2017; 21:855-860
- Söderström L, Rosenblad A, Bergkvist L, Frid H, Thors Adolfsson E. Dietary advice and oral nutritional supplements do not increase survival in older malnourished adults: a multicentre randomised controlled trial. Upsala Journal of Medical Sciences 2020; 125:240-249
- Detail
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Search Plan and Results: MiOA: Intervention Oral Nutrition Supplements 2023
In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on hospital readmissions?-
Conclusion
Oral nutrition supplements likely have little to no effect on hospital readmissions.
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Grade: Low (C)
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.
-
Evidence Summary: In older adults discharged from acute care to the community, what is the effect of oral nutrition supplements on hospital readmissions?
- Detail
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Worksheets
- Edington J, Barnes R, Bryan F, Dupree E, Frost G, Hickson M, Lancaster J, Mongia S, Smith J, Torrance A, West R, Pang F, Coles S. A prospective randomised controlled trial of nutritional supplementation in malnourished elderly in the community: clinical and health economic outcomes. Clinical Nutrition (Edinburgh, Scotland) 2004; 23:195-204
- Gade J, Beck A, Andersen H, Christensen B, Rønholt F, Klausen T, Vinther A, Astrup A. Protein supplementation combined with low-intensity resistance training in geriatric medical patients during and after hospitalisation: a randomised, double-blind, multicentre trial. The British Journal of Nutrition 2019; 122:1006-1020
- McMurdo M, Price R, Shields M, Potter J, Stott D. Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial. Journal of the American Geriatrics Society 2009; 57:2239-2245
- Detail
-
Search Plan and Results: MiOA: Intervention Oral Nutrition Supplements 2023
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Conclusion