• Assessment
    What is the relationship between chronic kidney disease and hypertension and hyperlipidemia? (2001 CD)
    • Conclusion

      The prevalence of hypertension and hyperlipidemia with risk for cardiovascular disease, coronary artery disease, and left ventricular hypertrophy is higher in chronic kidney disease compared to the general population. Aggressive treatment of hypertension with a goal of <135/85 mm Hg without proteinuria and <125/75 mm Hg with proteinuria >1g protein/24 hours with medications and restriction of dietary sodium to 1 to 3 g per day will slow the progression of kidney disease and reduce the risk of cardiovascular disease. Serum potassium should be monitored because of the effect of some antihypertensive agents on potassium excretion.



    • Grade: II
      • Grade I means there is Good/Strong evidence supporting the statement;
      • Grade II is Fair;
      • Grade III is Limited/Weak;
      • Grade IV is Expert Opinion Only;
      • Grade V is Not Assignable.
      • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
      • Moderate (B) means we are moderately confident in the effect estimate;
      • Low (C) means our confidence in the effect estimate is limited;
      • Very Low (D) means we have very little confidence in the effect estimate.
      • Ungraded means a grade is not assignable.