Replacing saturated fat intake with either unsaturated fat or carbohydrates, principally contributed by fruits, vegetables and grains, is effective in reducing LDL-cholesterol. A diet rich in monounsaturated fat may be effective in also reducing serum triglycerides.

• Grade I means there is Good/Strong evidence supporting the statement;
• Grade II is Fair;
• Grade III is Limited/Weak;
• Grade IV is Expert Opinion Only;
• Grade V is Not Assignable.
• High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
• Moderate (B) means we are moderately confident in the effect estimate;
• Low (C) means our confidence in the effect estimate is limited;
• Very Low (D) means we have very little confidence in the effect estimate.
• Ungraded means a grade is not assignable.