Disorders of Lipid Metabolism

DLM-SF: Butter (2021)

• Intervention
  In adults with or without cardiovascular disease, what is the association between butter intake and all-cause mortality?

  • Conclusion

    In adults with or without cardiovascular disease, a higher intake of butter compared to a lower intake of butter may not be associated with all-cause mortality.

  • Grade: Low (C)
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with or without cardiovascular disease, what is the association between butter intake and all-cause mortality?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • O'Sullivan TA, Hafekost K, Mitrou F, Lawrence D. Food sources of saturated fat and the association with mortality: a meta-analysis. American Journal of Public Health 2013; 103:31-42
  • Search Plan and Results: DLM-SF: Source of Saturated Fat (Observational) (2021)
     
  In adults with or without cardiovascular disease, what is the association between butter intake and any cardiovascular-related outcomes?

  • Conclusion

    In adults with or without cardiovascular disease, a higher intake of butter compared to a lower intake of butter may not be associated with an increased risk for any cardiovascular-related outcomes.

  • Grade: Low (C)
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: In adults with or without cardiovascular disease, what is the association between butter intake and any cardiovascular disease?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Jakobsen M, Trolle E, Outzen M, Mejborn H, Grønberg M, Lyndgaard C, Stockmarr A, Venø S, Bysted A. Intake of dairy products and associations with major atherosclerotic cardiovascular diseases: a systematic review and meta-analysis of cohort studies. Scientific Reports 2021; 11:1303
      • Patterson E, Larsson S, Wolk A, Åkesson A. Association between dairy food consumption and risk of myocardial infarction in women differs by type of dairy food. Journal of Nutrition 2013; 143:74-79
      • Pimpin L, Wu JHY, Haskelberg H, Del Gobbo L, Mozaffarian D. Is butter back? A systematic review and meta-analysis of butter consumption and risk of cardiovascular disease, diabetes, and total mortality. PLoS One 2016; 11:
      • von Ruesten A, Feller S, Bergmann M, Boeing H. Diet and risk of chronic diseases: results from the first 8 years of follow-up in the EPIC-Potsdam study. European Journal of Clinical Nutrition 2013; 67:412-419
  • Search Plan and Results: DLM-SF: Source of Saturated Fat (Observational) (2021)