• Basic Research
    Homocysteine, Folate, B-12 (Hyperlipidemia 2001)
    • Conclusion

      Observational studies (cohort, case control, population) show an inverse relationship between serum homosysteine and the incidence of coronary heart disease (CHD).  Studies show that low folate levels and high homosysteine levels are associated with an increased incidence of CHD, whereas high serum folate and low homoscysteine levels are not associated with an increase in CHD.  No experimental (Randomized Control Trials) have been done to determine the effects of folate supplementation on incidence of CHD.

      This information is from the 2001 Hyperlipidemia project.