DLM: Soy (2001)
The ADA 2001 Hyperlipidemia MNT Evidence-based guide for practice was originally published in a compact disk (CD) format. This 2001 project was published to the online Evidence Analysis Library for the benefit of ADA members, even though it does not follow the current online format and may be missing some of the components (all of the components of current evidence analysis include: question, conclusion, grade, search plan and results, evidence summary, overview table, worksheets, and quality check lists.)
Soy (Hyperlipidemia 2001)
Studies focusing on the ingestion of diets containing soy protein as compared with control diets (that did not contain soy protein) demonstrated that soy protein is effective in lowering serum total cholesterol, LDL-Cholesterol, and triglycerides ~10% in individuals with hyperlipidemia. Greater decreases in serum lipids were demonstrated with greater amounts of soy protein, however significant decreases were seen with 25 grams of soy protein per day. No Random Control Trials (studies with a control and experimental group that show cause and effect) of soy protein have been done to evaluate the risk of coronary heart disease (CHD).
This information is from the 2001 Hyperlipidemia project.
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
Evidence Summary: Soy (Hyperlipidemia 2001)
- Quality Rating Summary
For a summary of the Quality Rating results, click here.
- Anderson JW, Johnstone BM, Cook-Newell ME. Meta-analysis of the effects of soy protein on serum lipids. N Engl J Med. 1995; 333:276-282.
- Baum JA, Teng H, Erdman JW, Weigel RM, Klein BP, Persky VW, Freels S, Surya P, Bakhit RM, Ramos E, Shay NF, Potter SM. Long-term intake of soy protein improves blood lipid profiles and increases mononuclear cell low-density -liproprotein receptor messenger RNA in hypercholesterolemic, postmenopausal women. Am J Clin Nutr 1998:68:545-551.
- Jenkins DJ, et.al. Metabolism. 2000;49:67-72