Disorders of Lipid Metabolism

DLM: Fiber (2007)

• Intervention
  What does the evidence indicate is the relationship between fiber intake and Coronary Heart Disease outcomes?

  • Conclusion

    Consuming diets high in total dietary fiber (greater than 25 grams per day) is associated with decreased risk for CHD and CVD.

  • Grade: II
    • Grade I means there is Good/Strong evidence supporting the statement;
    • Grade II is Fair;
    • Grade III is Limited/Weak;
    • Grade IV is Expert Opinion Only;
    • Grade V is Not Assignable.
    • High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
    • Moderate (B) means we are moderately confident in the effect estimate;
    • Low (C) means our confidence in the effect estimate is limited;
    • Very Low (D) means we have very little confidence in the effect estimate.
    • Ungraded means a grade is not assignable.
  • Evidence Summary: What does the evidence indicate is the relationship between fiber intake and Coronary Heart Disease outcomes?
    • Detail
    • Quality Rating Summary
      For a summary of the Quality Rating results, click here.
    • Worksheets
      • Bazzano, L.A., He, J., Ogden, L.G., Loria, C.M., Whelton, P.K. Dietary fiber intake and reduced risk of coronary heart disease in us men and women. Arch Intern Med. 2003; 163:1897-1904.
      • Liu S, Stampfer MJ, Hu FB, Giovannucci E, Rimm E, Manson JE, Hennekens CH, Willett WC. Whole-grain consumption and risk of coronary heart disease: Results from the Nurses’ Health Study. Am J Clin Nutr. 1999; 70: 412-419.
      • Liu, S., Buring, J., Sesso, H., Rimm, E., Willett, W., Manson, J. A prospective study of dietary fiber intake and risk of cardiovascular disease among women. J Am Coll Cardiol 2002,39:49-56
      • Merchant AT, Hu FB, Spieglman D, Willett WC, Rimm EB, Ascherio A. Dietary fiber reduces peripheral arterial disease risk in men. J Nutr. 2003;133: 3658-3663.
      • Pereira MA, O'Reilly E, Augustsson K, Fraser GE, Goldbourt U, Heitmann BL, Hallmans G, Knekt P, Liu S, Pietinen P, Spiegelman D, Stevens J, Virtamo J, Willett WC, Ascherio A.. Dietary fiber and risk of coronary heart disease. Arch Intern Med. 2004; 164: 370-376.
      • Van Horn L. Fiber, lipids, and coronary heart disease. Circulation. 1997;95:2701-2704.
      • Wolk J, Mason JE, Stampfer MJ, et al. Long-term intake of dietary fiber and decreased risk of coronary heart disease among women. JAMA. 1999;281:1998-2004.
  • Search Plan and Results: DLM: Fiber & DLM 2004