Under isocaloric conditions, what is the impact of changing the quality and composition of macronutrient (carbohydrates, proteins and dietary fat) on LDL-cholesterol levels in normolipidimic and hyperlipidemic individuals?
Replacing saturated fat intake with either unsaturated fat or carbohydrates, principally contributed by fruits, vegetables and grains, is effective in reducing LDL-cholesterol. A diet rich in monounsaturated fat may be effective in also reducing serum triglycerides.
- Grade I means there is Good/Strong evidence supporting the statement;
- Grade II is Fair;
- Grade III is Limited/Weak;
- Grade IV is Expert Opinion Only;
- Grade V is Not Assignable.
- High (A) means we are very confident that the true effect lies close to that of the estimate of the effect;
- Moderate (B) means we are moderately confident in the effect estimate;
- Low (C) means our confidence in the effect estimate is limited;
- Very Low (D) means we have very little confidence in the effect estimate.
- Ungraded means a grade is not assignable.